Fosaprepitant for Injection

FOSAVI for Injection is an antiemetic medication used primarily to prevent nausea and vomiting associated with chemotherapy. It belongs to a class of drugs known as neurokinin-1 (NK1) receptor antagonists. Here are the key uses of FOSAVI for Injection:

1. Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV):

   - It is used in combination with other antiemetic agents (like a serotonin 5-HT3 antagonist and a corticosteroid) to prevent both acute and delayed nausea and vomiting caused by highly and moderately emetogenic chemotherapy.

2. Prevention of Postoperative Nausea and Vomiting (PONV):

   - In some cases, FOSAVI may be used to prevent nausea and vomiting following surgery.

FOSAVI is typically administered as a single intravenous dose before the start of chemotherapy. It is a prodrug of aprepitant, meaning it is converted into aprepitant in the body, which then exerts its antiemetic effects by blocking the action of substance P, a neuropeptide associated with vomiting.

This medication should be used under the supervision of a healthcare professional, and it is usually part of a larger antiemetic regimen to maximize its effectiveness.