5-Fluorouracil, available in topical formulations for treating actinic keratoses and superficial basal cell carcinomas, provides effective management when conventional methods are impractical. With a 5% strength, it targets multiple lesions or challenging treatment sites. Additionally, Fluorouracil injection serves in palliative care for various cancers, including those affecting the colon, esophagus, stomach, breast, head and neck, and more. Its mechanism inhibits DNA synthesis, thereby impeding cancer cell growth. Consult healthcare professionals for personalized treatment plans, ensuring optimal outcomes.